Fast similarity measure of SWATH-MS by Cosine Similarity of Random Pairs(CS-RP)
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We proposed a new similarity measure on MS2 (tandem mass spectrometry) data - cosine similarity of random pairs(CS-RP). This method reduces time cost of intensity-wise retention time alignment by SWATH or other DIA-MS2 data. The results of CS-RP shared similar results from the retention time alignments with MS1-based method.